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IUL Biotechnology Series, 9 |
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by Miguel A.R.B. Castanho (Editor) |
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Edition: First |
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Book
Details:
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| Reviews |
| Reviewer: Joel Schneider, Editor in Chief,
Biopolymers-Peptide Science, Professor
of Chemistry and Biochemistry, |
| Professor
Castanho, a leader in the field of peptide-membrane
interactions has assembled a comprehensive collection of chapters that
defines
the field. The biophysics that governs the interplay between peptides
and
membranes is examined via in-depth discussions of the tools used to
study these
events and biological examples in which these processes play key roles.
The
book is assembled in a logical manner beginning with chapters that
critically
examine computational and the biophysical methods used to study
peptide-membrane interactions. Light scattering, |
Edited by Miguel A. R. B. Castanho, Institute of Biochemistry, School of Medicine, University of Lisbon, Portugal.
Among all sectors of peptide science, membrane-active peptidology is probably the most promising and fast growing. Membrane-active peptides are a challenge for their involvement in highly heterogeneous systems, the biological membranes. Surface chemistry at the lipid water interface and molecular events in a confined medium such as the lipid bilayer (not exactly 2D, not exactly 3D) are quite appealing, almost irresistible mainly to physical chemists and physical biochemists, whether to study structural aspects of peptide conformation and supra-molecular organization of peptides and/or lipids, or the thermodynamics and kinetics associated to the molecular dynamics of microheterogenous systems. The evolution of biophysical techniques with constant improvement in time and space resolution enables increasingly detailed insights.